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Snoring is aging you faster, says study; Take ways to reverse sleep apnea damage

March 17, 2022
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Untreated obstructive sleep apnea can lead to other diseases that accelerate aging and cause premature death.

Photo: iStock

We all know from various sources that Obstructive Sleep Apnea (OSA) – sometimes manifested in a rather rude Snoring Sound – is associated with a louder Risk of hypertension, Heart attacks, strokes, diabetes and many other chronic conditions. We know about the sad loss of talented musician Bappi Lahiri, who died just a month ago in Mumbai due to OSA news, confirmed by his attending physician.
But now, researchers at the University of Missouri School of Medicine have found that untreated OSA also accelerates the biological aging process and that (thankfully) adequate treatment slows the trend or possibly reverses it.

what is Obstructive sleep apnea?

Sleep apnea is a disorder characterized by repetitive pauses in breathing during sleep, caused by respiratory occlusion (obstructive sleep apnea) or altered control of respiration (central sleep apnea). Obstructive sleep apnea (OSA) affects 22 million people in the United States and is associated with a higher risk of hypertension, heart attacks, strokes, diabetes and many other chronic conditions. A study by the All India Institute of Medical Sciences – aka AIIMS New Delhi has shown that the risk factors and prevalence for OSA in India are similar to those in the West, which is in contrast to the results of some previous reports that a had strong inclusion. bias.
The latest study on the aging threat angle for OSA was recently published in the European Respiratory Journal.

What is age acceleration?

Aging acceleration test includes a blood test that analyzes DNA and uses an algorithm to measure a person’s biological age, reports EurekaAlerts.com.

The phenomenon of a biological age of a person exceeding their chronological age is called “epigenetic age acceleration“, and is associated with general mortality and with chronic diseases.

“Age acceleration is not unique to OSA, it can be caused by a variety of environmental factors such as smoking, poor nutrition or pollution,” said Rene Cortese, PhD, assistant professor in the Department of Child Health and the Department of Obstetrics, Gynecology and Women d. ‘Bless you.

“In Western culture, it is not uncommon for people to experience epigenetic aging, but we wanted to know how OSA affects systemic aging compared to those who do not suffer from this condition.”

Cortese’s team exposed other study authors, namely. MU colleagues Leila Kheirandish-Gozal, MD, director of the Child Health Research Institute; and David Gozal, MD, Marie M. and Harry L. Smith Endowed Presidency of Child Health.

Prof. Dr. David Gozal, Prof. Dr. Sina A. Gharib and Dr. Rene Cortese Leads This Special Issue “#Molecular Ins… t.co/vuXc22n6Qv

– ANI (@ANI) February 15, 2022

How was the study conducted?

The researchers studied 16 adult non-smokers diagnosed with OSA and compared them with eight control abilities without assessing the condition for assessing the impact of OSA on epigenetic aging over a one-year period.

After a baseline blood test, the OSA group received continuous positive air pressure (CPAP) Treatment for one year. After one year of CPAP treatment, the group was tested again.

What is CPAP?

According to this definition by Meri Fitzgerald Hospital and Baylor College of Medicine (USA), “Continuous Positive Airway Pressure (CPAP) is a type of positive airway pressure in which airflow is introduced into the airways to maintain a continuous pressure for constant Stents the airways, in people who breathe spontaneously.Patients inhale air through the nose, and air travels through the nasopharynx, oropharynx, into the larynx, trachea, bronchi, bronchioles, and finally into the alveoli.Sometimes , Portions of the Difficulty breathing can be blocked by excess tissue, tonsillar overgrowth, poor tone of muscles, fat excess, secretions among others. The forced air supplied by the CPAP helps keep the respiratory tract patent and prevents collapse.

Last day of the World Sleep Conference – Rome honored us with its glorious history and hospitality in science … t.co/pRJud27God

– ANI (@ANI) March 16, 2022

“Our results found that OSA-induced sleep disorders and lower oxygen levels during sleep promoted faster biological age acceleration compared with the control group. “Age, while age-accelerating trends do not. Change for the control group. Our results suggest that biological age-acceleration is at least partially reversible when effective treatment of OSA is implemented,” Cortese said.

Cortese said the key to CPAP’s success in extending the age acceleration is a strong inhalation for the device to be used for at least four hours a night. It is not clear how age acceleration affects clinical outcomes and how it applies to other risk groups or children with OSA.

Fighting Stigma: Sleep Apnea Accelerates Aging, But Treatment Can Avoid It – EurekAlert !: Image: Rene Cortese,… t.co/ojxIS0jAuR

– ANI (@ANI) March 10, 2022

“Because children with OSA are treated differently than adults, this research raises many questions,” Cortese said. “We need to learn more about the mechanisms and biology behind these findings. It is very exciting and thought-provoking research.”

Treatment options in India:

Some reputable hospitals have dedicated sleep clinic setups. Apollo TeleHealth (an organization that uses state-of-the-art technologies) claims to have an OSA treatment program that includes home / hospital screening and diagnosis using the latest technology-based devices that are cost-effective and convenient. “For treatment, CPAP devices with connected facilities are provided to remotely monitor treatment therapy to obtain better treatment results. In addition, there is also a back-end support team with sleep technicians, sleep coaches and counselors to help educate and guide patients during each step of the treatment program. Through this dedicated program, we aim to bring more patients in and significantly reduce or eliminate the burden of sleep apnea. Sleep disorders and obesity are added to the list of NCDs. ” , said. Vikram Thaploo, CEO of Apollo TeleHealth.

Dr. Ayesha Nazneen – Chief Medical Officer, Apollo TeleHealth said, “Sleep apnea is a serious chronic condition that affects far more than just sleep – it affects patients’ quality of life and overall health. ‘Gutt Nidra’ Program, we believe we can make it significantly easier to manage patients affected with obstructive sleep apnea and increase the number of patients we can treat on a daily basis. All one has to do is fill out a questionnaire, then a sleep expert joins in to help diagnose, advise, and interpret various clinical reports that follow from the installation of a connected CPAP device at home. The program will also support the patient with constant treatment compliance monitoring and lifestyle management. This innovative new program can help the medical community as a whole address these widespread silent killers directly in hopes of saving more lives and raising awareness of this deadly disease.

World Sleep Day 2022:

World Sleep Day – which is held on the Friday before the annual spring equinox of every year – is an event that is meant to be a sleep celebration and a call to action on important issues related to sleep, including medicine, education, social aspects and driving. This year it falls on Friday, March 18, 2022, and next year it will be observed on Friday, March 17, 2023. The cumulative theme and slogan of this year’s World Sleep Day is “Quality Sleep, Sound Mind, Happy World”.

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