World number one Luke Humphries hit the first Premier League nine-darter of 2025 but was beaten by Rob Cross.
Humphries hit two 180s before a 141 checkout on night five in Brighton to go 2-0 ahead.
The 30-year-old, who was seeking his third nightly win of the campaign, ended up losing 6-4 in the quarter-finals to his fellow Englishman.
It was the 17th perfect leg in the Premier League since its inception in 2005.
But 2018 world champion Cross hit seven 180s of his own and averaged 111.19 as he grabbed the victory.
Quarter-finals
Gerwyn Price 3-6 Michael van Gerwen
Luke Littler 6-5 Chris Dobey
Rob Cross 6-4 Luke Humphries
Stephen Bunting v Nathan Aspinall
Premier League Darts is played across 16 initial weeks in the league stage with quarter-finals, semi-finals and a final each night.
Each of the eight players is guaranteed to face the other seven in the quarter-finals in weeks 1-7 and 9-15, with weeks 8 and 16’s fixtures done off the table. It means we will get fourth v fifth in Sheffield on the final league-stage night, with the play-off spots potentially on the line.
Players earn two points per quarter-final win, an additional point if they win their semi-final and five for winning the night.
The top four players after the group stage progress to the play-off night at London’s O2 Arena on 23 May, with first facing fourth and second against third in a best-of-19-leg match. The final, which is the best of 21 legs, follows.
If players are level on points after the 16 weeks then places are decided by nights won and then matches won.
Nottingham, 13 March, 19:00 GMT
Luke Humphries v Luke Littler
Rob Cross v Chris Dobey
Stephen Bunting v Gerwyn Price
Nathan Aspinall v Michael van Gerwen
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